I have a flare up in my lower back that I tried multiple things for 3 years to alleviate the pain. Physical Therapy, Chiropractic, Exercise, Muscle Relaxers, Natural solutions, Nerve medicines, etc  Nothing worked, but one month after starting a GLP-1 I noticed my spasms and pain was gone.  I did let my doctor and neurologist know.  I also did some research online to see that others were noticing similar things that had MS, Rheumatoid arthritis, and other ailments where inflammation is present. 
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iConquerMS